Hydrogen sulphide induces μ opioid receptor-dependent analgesia in a rodent model of visceral pain

BACKGROUND: Hydrogen sulphide (H(2)S) is a gaseous neuro-mediator that exerts analgesic effects in rodent models of visceral pain by activating K(ATP )channels. A body of evidence support the notion that K(ATP )channels interact with endogenous opioids. Whether H(2)S-induced analgesia involves opioi...

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Autors principals: Distrutti, Eleonora, Cipriani, Sabrina, Renga, Barbara, Mencarelli, Andrea, Migliorati, Marco, Cianetti, Stefano, Fiorucci, Stefano
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908066/
https://ncbi.nlm.nih.gov/pubmed/20540729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-36
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