Aging Exacerbates Depressive-like Behavior in Mice in Response to Activation of the Peripheral Innate Immune System

Exposure to peripheral infections may be permissive to cognitive and behavioral complications in the elderly. We have reported that peripheral stimulation of the innate immune system with lipopolysaccharide (LPS) causes an exaggerated neuroinflammatory response and prolonged sickness behavior in age...

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Bibliografiske detaljer
Main Authors: Godbout, Jonathan P, Moreau, Maïté, Lestage, Jacques, Chen, Jing, Sparkman, Nathan L, O’Connor, Jason, Castanon, Nathalie, Kelley, Keith W, Dantzer, Robert, Johnson, Rodney W
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907915/
https://ncbi.nlm.nih.gov/pubmed/18075491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301649
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