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Structural requirements for C. elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies
The activity of C. elegans scavenger decapping enzyme (DcpS) on its natural substrates and dinucleotide cap analogues modified in the nucleoside’s base or ribose moiety, has been examined. All tested dinucleotides were specifically cleaved between β and γ phosphate groups in the triphosphate chain....
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907653/ https://ncbi.nlm.nih.gov/pubmed/20546305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07709.x |
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