Structural requirements for C. elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies

The activity of C. elegans scavenger decapping enzyme (DcpS) on its natural substrates and dinucleotide cap analogues modified in the nucleoside’s base or ribose moiety, has been examined. All tested dinucleotides were specifically cleaved between β and γ phosphate groups in the triphosphate chain....

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Main Authors: Wypijewska, Anna, Bojarska, Elzbieta, Stepinski, Janusz, Jankowska-Anyszka, Marzena, Jemielity, Jacek, Davis, Richard E., Darzynkiewicz, Edward
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907653/
https://ncbi.nlm.nih.gov/pubmed/20546305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07709.x
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