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Reexamining Alzheimer's Disease: Evidence for a Protective Role for Amyloid-β Protein Precursor and Amyloid-β

Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized clinically by cognitive decline and pathologically by the accumulation of amyloid-β-containing senile plaques and neurofibrillary tangles. A great deal of attention has focused on amyloid-β as the major pathogeni...

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Autors principals: Castellani, Rudy J., Lee, Hyoung-gon, Siedlak, Sandra L., Nunomura, Akihiko, Hayashi, Takaaki, Nakamura, Masao, Zhu, Xiongwei, Perry, George, Smith, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907530/
https://ncbi.nlm.nih.gov/pubmed/19584435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1151
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