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Increased Renin Production in Mice with Deletion of PPARγ in Juxtaglomerular Cells
We found recently that endogenous (free fatty acids) and pharmacological (thiazolidinediones) agonists of nuclear receptor Peroxisome Proliferator-Activated Receptor-γ (PPARγ) stimulate renin transcription. In addition, the renin gene was identified as a direct target of PPARγ. The mouse renin gene...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907524/ https://ncbi.nlm.nih.gov/pubmed/20065157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.138800 |
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