Hypotonicity-Induced Renin Exocytosis from Juxtaglomerular Cells Requires Aquaporin-1 and Cyclooxygenase-2

The mechanism by which extracellular hypotonicity stimulates release of renin from juxtaglomerular (JG) cells is unknown. We hypothesized that osmotically induced renin release depends on water movement through aquaporin-1 (AQP1) water channels and subsequent prostanoid formation. We recorded membra...

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Detalhes bibliográficos
Main Authors: Friis, Ulla G., Madsen, Kirsten, Svenningsen, Per, Hansen, Pernille B.L., Gulaveerasingam, Ambika, Jørgensen, Finn, Aalkjær, Christian, Skøtt, Ole, Jensen, Boye L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754103/
https://ncbi.nlm.nih.gov/pubmed/19628672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008090944
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