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THE EFFECTS OF GLYCATION ON THE BINDING OF HUMAN SERUM ALBUMIN TO WARFARIN AND L-TRYPTOPHAN

Diabetes leads to elevated levels of glucose in blood which, in turn, can lead to the non-enzymatic glycation of serum proteins such as human serum albumin (HSA). It has been suggested that this increase in glycation can alter the ability of HSA to bind to drugs and other small solutes. This study u...

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Detalhes bibliográficos
Main Authors: Joseph, K.S., Hage, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907420/
https://ncbi.nlm.nih.gov/pubmed/20537832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2010.04.035
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