Neutralizing TIMP1 Restores Fecundity in a Rat Model of Endometriosis and Treating Control Rats with TIMP1 Causes Anomalies in Ovarian Function and Embryo Development

Human and rat endometriotic lesions synthesize and secrete tissue inhibitor of metalloproteinase 1 (TIMP1). More TIMP1 localizes in the ovarian theca in an established rat model for endometriosis (Endo) when compared to surgical controls (Sham). We hypothesized that endometriotic TIMP1 secreted into...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stilley, Julie A.W., Birt, Julie A., Nagel, Susan C., Sutovsky, Miriam, Sutovsky, Peter, Sharpe-Timms, Kathy L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for the Study of Reproduction, Inc. 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907283/
https://ncbi.nlm.nih.gov/pubmed/20410455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.083287
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