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DEVELOPMENTAL EXPOSURE OF FETAL OVARIES AND FETAL GERM CELLS TO ENDOMETRIOSIS CAUSES DIFFERENTIAL GENE EXPRESSION IN PRE-IMPLANTATION EMBRYOS OF FIRST AND SECOND GENERATION EMBRYOS OFFSPRING IN AN ENDOMETRIOSIS MODEL

OBJECTIVE: Characterize multigenerational gene expression anomalies in 8-cell stage embryos associated with developmental exposure to endometriosis. DESIGN: Using an endometriosis model in rats (F0 founder generation), evaluate gene expression in F1 (fetal exposure) and F2 (fetal germ cell exposure)...

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Detalhes bibliográficos
Main Authors: Birt, Julie A., Taylor, Kristen H., Davis, J. Wade, Sharpe-Timms, Kathy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847911/
https://ncbi.nlm.nih.gov/pubmed/23954358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2013.07.007
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