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Inhibition of BACE1 for therapeutic usein Alzheimer's disease

Since BACE1 was reported as the β-secretase in Alzheimer's disease (AD) over ten years ago, encouraging progress has been made toward understanding the cellular functions of BACE1. Genetic studies have further confirmed that BACE1 is essential for processing amyloid precursor protein (APP) at t...

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Библиографические подробности
Главные авторы: Luo, Xiaoyang, Yan, Riqiang
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907124/
https://ncbi.nlm.nih.gov/pubmed/20661410
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