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Elusive transition state of alcohol dehydrogenase unveiled

For several decades the hydride transfer catalyzed by alcohol dehydrogenase has been difficult to understand. Here we add to the large corpus of anomalous and paradoxical data collected for this reaction by measuring a normal (> 1) 2° kinetic isotope effect (KIE) for the reduction of benzaldehyde...

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Bibliografski detalji
Glavni autori: Roston, Daniel, Kohen, Amnon
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906880/
https://ncbi.nlm.nih.gov/pubmed/20457944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000931107
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