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Elusive transition state of alcohol dehydrogenase unveiled
For several decades the hydride transfer catalyzed by alcohol dehydrogenase has been difficult to understand. Here we add to the large corpus of anomalous and paradoxical data collected for this reaction by measuring a normal (> 1) 2° kinetic isotope effect (KIE) for the reduction of benzaldehyde...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906880/ https://ncbi.nlm.nih.gov/pubmed/20457944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000931107 |
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