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Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1β secretion
In healthy monocytes, Toll-like receptor (TLR) engagement induces production of reactive oxygen species (ROS), followed by an antioxidant response involved in IL-1β processing and secretion. Markers of the antioxidant response include intracellular thioredoxin and extracellular release of reduced cy...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906851/ https://ncbi.nlm.nih.gov/pubmed/20445104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000779107 |
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