ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way

IL-1β and IL-18 are crucial mediators of inflammation, and a defective control of their release may cause serious diseases. Yet, the mechanisms regulating IL-1β and IL-18 secretion are partially undefined. Both cytokines are produced as inactive cytoplasmic precursors. Processing to the active form...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Piccini, Alessandra, Carta, Sonia, Tassi, Sara, Lasiglié, Denise, Fossati, Gianluca, Rubartelli, Anna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430360/
https://ncbi.nlm.nih.gov/pubmed/18523012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709684105
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