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Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation
The TIM22 protein import pathway mediates the import of membrane proteins into the mitochondrial inner membrane and consists of two intermembrane space chaperone complexes, the Tim9-Tim10 and Tim8-Tim13 complexes. To facilitate mechanistic studies, we developed a chemical-genetic approach to identif...
Tallennettuna:
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906835/ https://ncbi.nlm.nih.gov/pubmed/20457929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914387107 |
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