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GroEL-induced topological dislocation of a substrate protein β-sheet core: a solution EPR spin–spin distance study
The Hsp60-type chaperonin GroEL assists in the folding of the enzyme human carbonic anhydrase II (HCA II) and protects it from aggregation. This study was aimed to monitor conformational rearrangement of the substrate protein during the initial GroEL capture (in the absence of ATP) of the thermally...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906716/ https://ncbi.nlm.nih.gov/pubmed/21479077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-010-0038-2 |
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