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RUNX REGULATION OF SPHINGOLIPID METABOLISM AND SURVIVAL SIGNALLING
The Runx genes (Runx1, 2 and 3) regulate cell fate in development and can operate as either oncogenes or tumour suppressors in cancer. The oncogenic potential of ectopic Runx expression has been demonstrated in transgenic mice that develop lymphoma in potent synergy with over-expressed Myc, and in e...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906707/ https://ncbi.nlm.nih.gov/pubmed/20587518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0726 |
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