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Flavin-containing monooxygenase-3: induction by 3-methylcholanthrene and complex regulation by xenobiotic chemicals in hepatoma cells and mouse liver

Flavin-containing monooxygenases often are thought not to be inducible but we recently demonstrated aryl hydrocarbon receptor (AHR)-dependent induction of FMO mRNAs in mouse liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (Celius et al., Drug Metab Dispos 36:2499, 2008). We now evaluated FMO ind...

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Detalhes bibliográficos
Main Authors: Celius, Trine, Pansoy, Andrea, Matthews, Jason, Okey, Allan B., Henderson, Marilyn C., Krueger, Sharon K., Williams, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906660/
https://ncbi.nlm.nih.gov/pubmed/20570689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.05.018
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