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Epigenetic silencing of CYP24 in the tumor microenvironment
Calcitriol (1,25 dihydroxycholecalciferol) has significant antitumor activity in vitro and in vivo in a number of tumor model systems. We developed a system for isolation of fresh endothelial cells from tumors and Matrigel environments which demonstrate that CYP24, the catabolic enzyme involved in v...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906617/ https://ncbi.nlm.nih.gov/pubmed/20304059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2010.03.046 |
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