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Epigenetic silencing of CYP24 in the tumor microenvironment

Calcitriol (1,25 dihydroxycholecalciferol) has significant antitumor activity in vitro and in vivo in a number of tumor model systems. We developed a system for isolation of fresh endothelial cells from tumors and Matrigel environments which demonstrate that CYP24, the catabolic enzyme involved in v...

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Détails bibliographiques
Auteurs principaux: Johnson, Candace S., Chung, Ivy, Trump, Donald L.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906617/
https://ncbi.nlm.nih.gov/pubmed/20304059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2010.03.046
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