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24-Hydroxylase in Cancer: Impact on Vitamin D-based Anticancer Therapeutics

The active vitamin D hormone 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) plays a major role in regulating calcium homeostasis and bone mineralization. 1,25(OH)(2)D(3) also modulates cellular proliferation and differentiation in a variety of cell types. 24-hydroxylase, encoded by the CYP24A1 gene, i...

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Detalhes bibliográficos
Main Authors: Luo, Wei, Hershberger, Pamela A., Trump, Donald L., Johnson, Candace S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686893/
https://ncbi.nlm.nih.gov/pubmed/23059474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2012.09.031
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