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24-Hydroxylase in Cancer: Impact on Vitamin D-based Anticancer Therapeutics
The active vitamin D hormone 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) plays a major role in regulating calcium homeostasis and bone mineralization. 1,25(OH)(2)D(3) also modulates cellular proliferation and differentiation in a variety of cell types. 24-hydroxylase, encoded by the CYP24A1 gene, i...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686893/ https://ncbi.nlm.nih.gov/pubmed/23059474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2012.09.031 |
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