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Silk-elastinlike protein polymers improve the efficacy of adenovirus thymidine kinase enzyme prodrug therapy of head and neck tumors
BACKGROUND: Adenoviral directed enzyme prodrug therapy is a promising approach for head and neck cancer gene therapy. Challenges with this approach however are transient gene expression and dissemination of viruses to distant organs. METHODS: We used recombinant silk-elastinlike protein copolymer (S...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906606/ https://ncbi.nlm.nih.gov/pubmed/20603862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1469 |
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