Silk-Elastinlike Protein Polymer Hydrogels for Localized Adenoviral Gene Therapy of Head and Neck Tumors

Vector dissemination, transient gene expression and rapid clearance are major obstacles to successful human gene therapy. In this study, we investigated the effect of silk-elastinlike protein polymer (SELP) hydrogels, on biodistribution and anticancer efficacy of adenoviral gene therapy in a head an...

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Detalhes bibliográficos
Main Authors: Greish, Khaled, Araki, Koji, Li, Daqing, O’Malley, Bert W., Dandu, Ramesh, Frandsen, Jordan, Cappello, Joseph, Ghandehari, Hamidreza
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818732/
https://ncbi.nlm.nih.gov/pubmed/19722557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm900356j
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