Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation

Asbestos carcinogenesis has been linked to the release of cytokines and mutagenic reactive oxygen species (ROS) from inflammatory cells. Asbestos is cytotoxic to human mesothelial cells (HM), which appears counterintuitive for a carcinogen. We show that asbestos-induced HM cell death is a regulated...

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Main Authors: Yang, Haining, Rivera, Zeyana, Jube, Sandro, Nasu, Masaki, Bertino, Pietro, Goparaju, Chandra, Franzoso, Guido, Lotze, Michael T., Krausz, Thomas, Pass, Harvey I., Bianchi, Marco E., Carbone, Michele
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906549/
https://ncbi.nlm.nih.gov/pubmed/20616036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006542107
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