Continuous Exposure to Chrysotile Asbestos Can Cause Transformation of Human Mesothelial Cells via HMGB1 and TNF-α Signaling

Malignant mesothelioma is strongly associated with asbestos exposure. Among asbestos fibers, crocidolite is considered the most and chrysotile the least oncogenic. Chrysotile accounts for more than 90% of the asbestos used worldwide, but its capacity to induce malignant mesothelioma is still debated...

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Detalhes bibliográficos
Main Authors: Qi, Fang, Okimoto, Gordon, Jube, Sandro, Napolitano, Andrea, Pass, Harvey I., Laczko, Rozalia, DeMay, Richard M., Khan, Ghazal, Tiirikainen, Maarit, Rinaudo, Caterina, Croce, Alessandro, Yang, Haining, Gaudino, Giovanni, Carbone, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814524/
https://ncbi.nlm.nih.gov/pubmed/24160326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.07.029
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