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Complement Regulator Factor H Mediates a Two-step Uptake of Streptococcus pneumoniae by Human Cells
Streptococcus pneumoniae, a human pathogen, recruits complement regulator factor H to its bacterial cell surface. The bacterial PspC protein binds Factor H via short consensus repeats (SCR) 8–11 and SCR19–20. In this study, we define how bacterially bound Factor H promotes pneumococcal adherence to...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906339/ https://ncbi.nlm.nih.gov/pubmed/20504767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142703 |
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