Vinculin Is a Dually Regulated Actin Filament Barbed End-capping and Side-binding Protein

The focal adhesion protein vinculin is an actin-binding protein involved in the mechanical coupling between the actin cytoskeleton and the extracellular matrix. An autoinhibitory interaction between the N-terminal head (Vh) and the C-terminal tail (Vt) of vinculin masks an actin filament side-bindin...

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Bibliographic Details
Main Authors: Le Clainche, Christophe, Dwivedi, Satya Prakash, Didry, Dominique, Carlier, Marie-France
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906333/
https://ncbi.nlm.nih.gov/pubmed/20484056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102830
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