Macrophage Fatty-acid Synthase Deficiency Decreases Diet-induced Atherosclerosis

Fatty acid metabolism is perturbed in atherosclerotic lesions, but whether it affects lesion formation is unknown. To determine whether fatty acid synthesis affects atherosclerosis, we inactivated fatty-acid synthase (FAS) in macrophages of apoE-deficient mice. Serum lipids, body weight, and glucose...

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Detaylı Bibliyografya
Asıl Yazarlar: Schneider, Jochen G., Yang, Zhen, Chakravarthy, Manu V., Lodhi, Irfan J., Wei, Xiaochao, Turk, John, Semenkovich, Clay F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Lipids
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906331/
https://ncbi.nlm.nih.gov/pubmed/20479009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.100321
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