cAMP Mediators of Pulsatile Insulin Secretion from Glucose-stimulated Single β-Cells

Pulsatile insulin release from glucose-stimulated β-cells is driven by oscillations of the Ca(2+) and cAMP concentrations in the subplasma membrane space ([Ca(2+)](pm) and [cAMP](pm)). To clarify mechanisms by which cAMP regulates insulin secretion, we performed parallel evanescent wave fluorescence...

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Bibliographic Details
Main Authors: Idevall-Hagren, Olof, Barg, Sebastian, Gylfe, Erik, Tengholm, Anders
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906294/
https://ncbi.nlm.nih.gov/pubmed/20498366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095992
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