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Hepatitis C Virus Non-structural Protein 3 (HCV NS3): A Multifunctional Antiviral Target
Hepatitis C virus non-structural protein 3 contains a serine protease and an RNA helicase. Protease cleaves the genome-encoded polyprotein and inactivates cellular proteins required for innate immunity. Protease has emerged as an important target for the development of antiviral therapeutics, but dr...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906261/ https://ncbi.nlm.nih.gov/pubmed/20457607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.125294 |
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