Hepatitis C Virus Non-structural Protein 3 (HCV NS3): A Multifunctional Antiviral Target

Hepatitis C virus non-structural protein 3 contains a serine protease and an RNA helicase. Protease cleaves the genome-encoded polyprotein and inactivates cellular proteins required for innate immunity. Protease has emerged as an important target for the development of antiviral therapeutics, but dr...

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Bibliographic Details
Main Authors: Raney, Kevin D., Sharma, Suresh D., Moustafa, Ibrahim M., Cameron, Craig E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906261/
https://ncbi.nlm.nih.gov/pubmed/20457607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.125294
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