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Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline [Image: see text]
BACKGROUND: Previous cross-sectional fMRI studies in subjects with prodromal Alzheimer disease (AD) have reported variable results, ranging from hypoactivation, similar to patients with AD, to paradoxically increased activation or hyperactivation compared to cognitively normal older individuals. We...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Academy of Neurology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905893/ https://ncbi.nlm.nih.gov/pubmed/20463288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181e3966e |
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