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Evidence of altered posteromedial cortical fMRI activity in subjects at risk for Alzheimer disease

The posteromedial cortices and other regions of the “default network” are particularly vulnerable to the pathology of Alzheimer disease (AD). In this study, we performed fMRI to investigate whether the presence of apolipoprotein E (APOE) ε4 allele and degree of memory impairment were associated with...

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Bibliographic Details
Main Authors: Pihlajamäki, Maija, O'Keefe, Kelly, Bertram, Lars, Tanzi, Rudolph E., Dickerson, Bradford C., Blacker, Deborah, Albert, Marilyn S., Sperling, Reisa A.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837131/
https://ncbi.nlm.nih.gov/pubmed/19571734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0b013e3181a785c9
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