Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and α-B-crystallin

We performed a proteomic investigation on primary cultures of neonatal rat cardiomyocytes after treatment with 10 nM endothelin-1 (ET1) for 48 h, an in vitro model for cardiac hypertrophy. Two-dimensional gel electrophoresis profiles of cell lysates were compared after colloidal Coomassie Blue stain...

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Detalhes bibliográficos
Main Authors: Agnetti, Giulio, Bezstarosti, Karel, Dekkers, Dick H.W., Verhoeven, Adrie J.M., Giordano, Emanuele, Guarnieri, Carlo, Caldarera, Claudio M., Van Eyk, Jennifer E., Lamers, Jos M.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905868/
https://ncbi.nlm.nih.gov/pubmed/18472024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.04.003
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