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Granzyme A activates another way to die
Granzyme A (GzmA) is the most abundant serine protease in killer cell cytotoxic granules. GzmA activates a novel programmed cell death pathway that begins in the mitochondrion, where cleavage of NDUFS3 in electron transport complex I disrupts mitochondrial metabolism and generates reactive oxygen sp...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905780/ https://ncbi.nlm.nih.gov/pubmed/20536557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0105-2896.2010.00902.x |
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