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Granzyme A activates another way to die

Granzyme A (GzmA) is the most abundant serine protease in killer cell cytotoxic granules. GzmA activates a novel programmed cell death pathway that begins in the mitochondrion, where cleavage of NDUFS3 in electron transport complex I disrupts mitochondrial metabolism and generates reactive oxygen sp...

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Detalles Bibliográficos
Autor Principal: Lieberman, Judy
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905780/
https://ncbi.nlm.nih.gov/pubmed/20536557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0105-2896.2010.00902.x
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