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BIOENGINEERED ARGINASE I INCREASES CASPASE-3 EXPRESSION OF HEPATOCELULAR AND PANCREATIC CARCINOMA CELLS DESPITE INDUCTION OF ARGININOSUCCINATE SYNTHETASE-1
BACKGROUND: Hepatocellular and pancreatic carcinomas are often auxotrophic for L-arginine, a semi-essential amino acid. The purpose of this study was to investigate cancer cell death using a significantly more active, cobalt-substituted bioengineered arginase. METHODS: Panc-1, a human pancreatic car...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905509/ https://ncbi.nlm.nih.gov/pubmed/20466402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.03.022 |
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