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Micro-RNA-181a Regulates Osteopontin Dependent Metastatic Function In Hepatocellular Cancer Cell Lines

BACKGROUND: OPN is a variably expressed secreted glycophosphoprotein that mediates hepatocellular cancer (HCC) growth and metastasis. MicroRNAs (miRNAs) may be responsible for variant OPN expression, interrupting translation by binding OPN messenger RNA (mRNA) 3′-untranslated regions (UTRs). METHODS...

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Detalhes bibliográficos
Main Authors: Bhattacharya, Syamal D., Garrison, Juline, Guo, Hongtao, Mi, Zhiyong, Markovic, Jovan, Kim, Victoria M., Kuo, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905491/
https://ncbi.nlm.nih.gov/pubmed/20576283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.05.007
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