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Mutation in MTO1 involved in tRNA modification impairs mitochondrial RNA metabolism in the yeast Saccharomyces cerevisiae

The yeast MTO1 gene encodes an evolutionarily conserved protein for the biosynthesis of the 5-carboxymethylaminomethyl group of cmnm(5)s(2)U in the wobble position of mitochondrial tRNA. However, mto1 null mutant expressed the respiratory deficient phenotype only when coupled with the C1409G mutatio...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Xinjian, Yan, Qingfeng, Guan, Min-Xin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905380/
https://ncbi.nlm.nih.gov/pubmed/19460296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2009.01.010
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