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Combination of the loss of cmnm(5)U34 with the lack of s(2)U(34) modifications of tRNA(Lys), tRNA(Glu) and tRNA(Gln) altered mitochondrial biogenesis and respiration
Yeast Saccharomyces cerevisiae MTO2, MTO1 and MSS1 genes encoded highly conserved tRNA modifying enzymes for the biosynthesis of cmnm(5)s(2)U(34) in mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). In fact, Mto1p and Mss1p are involved in the biosynthesis of the cmnm(5) group (cmnm(5)U34), while Mt...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818684/ https://ncbi.nlm.nih.gov/pubmed/20004207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.12.002 |
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