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Hypomodification of the Wobble Base in tRNA(Glu), tRNA(Lys), and tRNA(Gln) Suppresses the Temperature-Sensitive Phenotype Caused by Mutant Release Factor 1

In Escherichia coli, release factor 1 (RF1) is one of two RFs that mediate termination; it specifically recognizes UAA and UAG stop codons. A mutant allele, prfA1, coding for an RF1 that causes temperature-sensitive (Ts) growth at 42°C, was used to select for temperature-resistant (Ts(+)) suppressor...

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Detalhes bibliográficos
Main Authors: Isak, Georgina, Rydén-Aulin, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648207/
https://ncbi.nlm.nih.gov/pubmed/19103926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01485-08
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