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Hypomodification of the Wobble Base in tRNA(Glu), tRNA(Lys), and tRNA(Gln) Suppresses the Temperature-Sensitive Phenotype Caused by Mutant Release Factor 1
In Escherichia coli, release factor 1 (RF1) is one of two RFs that mediate termination; it specifically recognizes UAA and UAG stop codons. A mutant allele, prfA1, coding for an RF1 that causes temperature-sensitive (Ts) growth at 42°C, was used to select for temperature-resistant (Ts(+)) suppressor...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2648207/ https://ncbi.nlm.nih.gov/pubmed/19103926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01485-08 |
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