Nuclear Modifier MTO2 Modulates the Aminoglycoside-Sensitivity of Mitochondrial 15S rRNA C1477G Mutation in Saccharomyces cerevisiae

The phenotypic manifestations of mitochondrial DNA (mtDNA) mutations are modulated by mitochondrial DNA haplotypes, nuclear modifier genes and environmental factors. The yeast mitochondrial 15S rRNA C1477G (P(R) or P(R) (454)) mutation corresponds to the human 12S rRNA C1494T and A1555G mutations, w...

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Main Authors: He, Xiangyu, Zhu, Xiaoyu, Wang, Xuexiang, Wang, Wei, Dai, Yu, Yan, Qingfeng
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858254/
https://ncbi.nlm.nih.gov/pubmed/24339937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081490
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