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The Fanconi Anemia Protein, FANCG, Binds to the ERCC1-XPF Endonuclease via its Tetratricopeptide Repeats and the Central Domain of ERCC1

There is evidence that Fanconi anemia (FA) proteins play an important role in the repair of DNA interstrand cross-links (ICLs), but the precise mechanism by which this occurs is not clear. One of the critical steps in the ICL repair process involves unhooking of the cross-link from DNA by incisions...

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Detalhes bibliográficos
Main Authors: Wang, Chuan, Lambert, Muriel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905376/
https://ncbi.nlm.nih.gov/pubmed/20518486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100584c
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