SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair

Progressive telomere attrition or deficiency of the protective shelterin complex elicits a DNA damage response as a result of a cell's inability to distinguish dysfunctional telomeric ends from DNA double-strand breaks. SNMIB/Apollo is a shelterin-associated protein and a member of the SMN1/PSO...

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Detalhes bibliográficos
Main Authors: Lam, Yung C, Akhter, Shamima, Gu, Peili, Ye, Jing, Poulet, Anaïs, Giraud-Panis, Marie-Josèphe, Bailey, Susan M, Gilson, Eric, Legerski, Randy J, Chang, Sandy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905253/
https://ncbi.nlm.nih.gov/pubmed/20551906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.58
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