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The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development

Conserved metallo β-Lactamase and β-CASP (CPSF-Artemis-Snm1-Pso2) domain nuclease family member SNM1B/Apollo is a shelterin-associated protein that localizes to telomeres through its interaction with TRF2. To study its in vivo role, we generated a knockout of SNM1B/Apollo in a mouse model. Snm1B/Apo...

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Main Authors: Akhter, Shamima, Lam, Yung C., Chang, Sandy, Legerski, Randy J.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719988/
https://ncbi.nlm.nih.gov/pubmed/20854421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00631.x
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