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Prp43p contains a processive helicase structural architecture with a specific regulatory domain

The DEAH/RNA helicase A (RHA) helicase family comprises proteins involved in splicing, ribosome biogenesis and transcription regulation. We report the structure of yeast Prp43p, a DEAH/RHA helicase remarkable in that it functions in both splicing and ribosome biogenesis. Prp43p displays a novel stru...

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Hlavní autoři: Walbott, Hélène, Mouffok, Saïda, Capeyrou, Régine, Lebaron, Simon, Humbert, Odile, van Tilbeurgh, Herman, Henry, Yves, Leulliot, Nicolas
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905241/
https://ncbi.nlm.nih.gov/pubmed/20512115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.102
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