The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis

Prp43p is a RNA helicase required for pre-mRNA splicing and for the synthesis of large and small ribosomal subunits. The molecular functions and modes of regulation of Prp43p during ribosome biogenesis remain unknown. We demonstrate that the G-patch protein Pfa1p, a component of pre-40S pre-ribosoma...

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Main Authors: Lebaron, Simon, Papin, Christophe, Capeyrou, Régine, Chen, Yan-Ling, Froment, Carine, Monsarrat, Bernard, Caizergues-Ferrer, Michèle, Grigoriev, Mikhail, Henry, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797057/
https://ncbi.nlm.nih.gov/pubmed/19927118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.335
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